The Truth About Metformin 500mg and B12 Deficiency: What Patients Must Know
Metformin 500 mg is highly effective for managing Type 2 diabetes and insulin resistance, but long-term use can sometimes lead to vitamin B12 deficiency. This happens because Metformin may reduce B12 absorption in the gut, especially after several years of continuous treatment.
Low B12 levels can cause fatigue, tingling in hands or feet, memory problems, and weakness—symptoms often mistaken for diabetes complications. The good news? B12 deficiency is preventable and treatable. Doctors recommend checking B12 levels every 1–2 years and taking supplements or fortified foods if levels drop.
If you’ve been on Metformin 500 mg for a long time, paying attention to B12 status is an important part of protecting your nerve health, energy levels, and overall well-being.
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